Genome microsatellite diversity within the Apicomplexa phylum.
Identifieur interne : 001233 ( Main/Exploration ); précédent : 001232; suivant : 001234Genome microsatellite diversity within the Apicomplexa phylum.
Auteurs : Juan Pablo Isaza [Colombie] ; Juan Fernando Alzate [Colombie]Source :
- Molecular genetics and genomics : MGG [ 1617-4623 ] ; 2016.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- genetics : Apicomplexa.
- Exons, Genetic Variation, Genome Size, Genome, Protozoan, Introns, Microsatellite Repeats.
Abstract
The Apicomplexa phylum groups include unicellular and obligate intracellular protozoan parasites with an apical complex used for attachment and invasion to host cells. In this study, we analyze single sequence repeats (SSRs) in the whole genome of 20 apicomplexan organisms that represent four different lineages within the phylum. Only perfect SSRs with at least 12 nucleotides and composed of 2-6 mers were included. To better understand the association of SSR types with the genomic regions, the SSRs were classified accordingly with the genomic location into exon, intron and intergenic categories. Our results showed heterogeneous SSRs density within the studied genomes. However, the most frequent SSRs types were di- and tri-nucleotide repeats. The former was associated with intergenic regions, while the latter was associated with exon regions.
DOI: 10.1007/s00438-016-1244-6
PubMed: 27590734
Affiliations:
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scheme="KwdFr" xml:lang="fr"><term>Apicomplexa (génétique)</term><term>Exons</term><term>Génome de protozoaire</term><term>Introns</term><term>Répétitions microsatellites</term><term>Taille du génome</term><term>Variation génétique</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Apicomplexa</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Apicomplexa</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Exons</term><term>Genetic Variation</term><term>Genome Size</term><term>Genome, Protozoan</term><term>Introns</term><term>Microsatellite Repeats</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Exons</term><term>Génome de protozoaire</term><term>Introns</term><term>Répétitions microsatellites</term><term>Taille du génome</term><term>Variation génétique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The Apicomplexa phylum groups include unicellular and obligate intracellular protozoan parasites with an apical complex used for attachment and invasion to host cells. In this study, we analyze single sequence repeats (SSRs) in the whole genome of 20 apicomplexan organisms that represent four different lineages within the phylum. Only perfect SSRs with at least 12 nucleotides and composed of 2-6 mers were included. To better understand the association of SSR types with the genomic regions, the SSRs were classified accordingly with the genomic location into exon, intron and intergenic categories. Our results showed heterogeneous SSRs density within the studied genomes. However, the most frequent SSRs types were di- and tri-nucleotide repeats. The former was associated with intergenic regions, while the latter was associated with exon regions.</div></front></TEI><affiliations><list><country><li>Colombie</li></country></list><tree><country name="Colombie"><noRegion><name sortKey="Isaza, Juan Pablo" sort="Isaza, Juan Pablo" uniqKey="Isaza J" first="Juan Pablo" last="Isaza">Juan Pablo Isaza</name></noRegion><name sortKey="Alzate, Juan Fernando" sort="Alzate, Juan Fernando" uniqKey="Alzate J" first="Juan Fernando" last="Alzate">Juan Fernando Alzate</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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